DUPIXENT is indicated in patients 6 years and older as add-on maintenance treatment for severe asthma with Type 2 inflammation characterised by:1

raised blood eosinophils (EOS)
and/or raised fraction of exhaled nitric oxide (FeNO)
who are inadequately controlled with  high-dose (ages 12 and older) and medium-to-high dose (ages 6 to 11) inhaled corticosteroids (ICS) plus another medicinal product for maintenance treatment

DUPIXENT is an injectable biologic that inhibits both
IL-4 and IL-13 signalling1–3

DUPIXENT is a biologic immunomodulator that targets more than one biomarker, unlike other available biologics1–3

Biological therapies aim to alter the immunopathogenesis leading to asthma rather than manage the downstream airway inflammation3

Other available biologics target either IgE or IL-5 whereas, DUPIXENT targets IL-4 and IL-31–3

SEE HOW DUPIXENT WORKS

What types of severe asthma patients can benefit from DUPIXENT?

The following criteria need to be met by your severe asthma patients:1

Patients 6 years and older with severe asthma

Patients with Type 2 inflammation, characterised by raised blood EOS and/or raised FeNO

Patients whose asthma is inadequately controlled with high-dose (ages 12 and older) and medium-to-high dose (ages 6 to 11) ICS plus another medicinal product for maintenance treatment

These severe asthma patients require treatment that will address their Type 2 patient profile

EXPLORE A TYPE 2 PATIENT PROFILE


Illustrative patient profiles. Not actual patients.

INTRODUCING THE DUPIXENT PRE-FILLED PEN

DUPIXENT can be administered via
a pre-filled pen or a syringe1

Mode of disease

Learn more about the triggers of severe asthma.

 


Find out more

Safety profile

Learn more about the safety profile of DUPIXENT.

 


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Efficacy results

Learn more about how DUPIXENT can improve asthma in adults and adolescents.



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    EOS, eosinophils; FeNO, fractional exhaled nitric oxide; ICS, inhaled corticosteroid; IL, interleukin.

    References

    1. DUPIXENT Summary of Product Characteristics, Date last accessed: May 2023.
    2. Gandhi NA, et al. Nat Rev Drug Discov. 2016;15:35–50.
    3. Krings JG, et al. J Allergy Clin Immunol Pract. 2019;7(5):1379–1392.
    4. Peters MC, et al. J Allergy Clin Immunol. 2014;133(2):388–394.
    5. Doran E, et al. Front Med. 2017;4:139.

MAT-XU-2204825 (v1.0) | Date of preparation: May 2023